Properties of MHC class I presented peptides that enhance immunogenicity.
T-cells have to recognize peptides presented on MHC molecules to be activated and elicit their effector functions. Several studies demonstrate that some peptides are more immunogenic than others and therefore more likely to be T-cell epitopes. We set out to determine which properties cause such diff...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-10-01
|
| Series: | PLoS Computational Biology |
| Online Access: | http://europepmc.org/articles/PMC3808449?pdf=render |