Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome

Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome

Objective: Internal clocks time behavior and physiology, including the gut microbiome, in a circadian (∼24 h) manner. Mismatch between internal and external time, e.g. during shift work, disrupts circadian system coordination promoting the development of obesity and type 2 diabetes (T2D). Conversely...

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Bibliographic Details
Main Authors: Baraa Altaha, Marjolein Heddes, Violetta Pilorz, Yunhui Niu, Elizaveta Gorbunova, Michael Gigl, Karin Kleigrewe, Henrik Oster, Dirk Haller, Silke Kiessling
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Circadian rhythm
SCN
Shift work
Microbiota
Short chain fatty acids
Bile acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001971

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http://www.sciencedirect.com/science/article/pii/S2212877822001971

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