Characterization of diseased primary human hepatocytes in an all-human cell-based triculture system
Abstract Liver diseases, including NAFLD, are a growing worldwide health concern. Currently, there is a lack of suitable in vitro models that sustain basic primary human hepatocyte (PHH) morphology and functionality while supporting presentation of disease-associated phenotypic characteristics such...
Main Authors: | Justin J. Odanga, Sharon M. Anderson, Erick K. Breathwaite, Sharon C. Presnell, Edward L. LeCluyse, Jingsong Chen, Jessica R. Weaver |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-024-57463-7 |
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