Production and characterization of single-chain variable fragment antibodies targeting the breast cancer tumor marker nectin-4

Production and characterization of single-chain variable fragment antibodies targeting the breast cancer tumor marker nectin-4

BackgroundNectin-4 is a novel biomarker overexpressed in various types of cancer, including breast cancer, in which it has been associated with poor prognosis. Current literature suggests that nectin-4 has a role in cancer progression and may have prognostic and therapeutic implications. The present...

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Bibliographic Details
Main Authors: Ching-Hsuan Liu, Sy-Jye Leu, Chi-Hsin Lee, Cheng-Yuan Lin, Wei-Chu Wang, Bor-Yu Tsai, Yu-Ching Lee, Chi-Long Chen, Yi-Yuan Yang, Liang-Tzung Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
phage display
single-chain variable fragment antibody
nectin-4
tumor marker
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1292019/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1292019/full

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