Different antibody-associated autoimmune diseases have distinct patterns of T follicular cell dysregulation

Different antibody-associated autoimmune diseases have distinct patterns of T follicular cell dysregulation

Abstract Autoantibodies are produced within germinal centers (GC), in a process regulated by interactions between B, T follicular helper (Tfh), and T follicular regulatory (Tfr) cells. The GC dysregulation in human autoimmunity has been inferred from circulating cells, albeit with conflicting result...

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Bibliographic Details
Main Authors: Filipa Ribeiro, Vasco C. Romão, Sara Rosa, Kátia Jesus, Ana Água-Doce, Sofia C. Barreira, Patrícia Martins, Susana Lopes da Silva, Ema Nobre, Maria João Bugalho, Válter R. Fonseca, João Eurico Fonseca, Luis Graca
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21576-8

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https://doi.org/10.1038/s41598-022-21576-8

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