Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy

Abstract Although pathological cardiac hypertrophy represents a leading cause of morbidity and mortality worldwide, our understanding of the molecular mechanisms underlying this disease is still poor. Here, we demonstrate that suppressor of IKKɛ (SIKE), a negative regulator of the interferon pathway...

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Bibliographic Details
Main Authors: Ke-Qiong Deng, Aibing Wang, Yan-Xiao Ji, Xiao-Jing Zhang, Jing Fang, Yan Zhang, Peng Zhang, Xi Jiang, Lu Gao, Xue-Yong Zhu, Yichao Zhao, Lingchen Gao, Qinglin Yang, Xue-Hai Zhu, Xiang Wei, Jun Pu, Hongliang Li
Format: Article
Language:English
Published: Nature Portfolio 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11432