Biochemical characterization of L-asparaginase isoforms from Rhizobium etli—the boosting effect of zinc

Biochemical characterization of L-asparaginase isoforms from Rhizobium etli—the boosting effect of zinc

L-Asparaginases, divided into three structural Classes, catalyze the hydrolysis of L-asparagine to L-aspartic acid and ammonia. The members of Class 3, ReAIV and ReAV, encoded in the genome of the nitrogen fixing Rhizobium etli, have the same fold, active site, and quaternary structure, despite low...

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Bibliographic Details
Main Authors: Joanna Sliwiak, Paulina Worsztynowicz, Kinga Pokrywka, Joanna I. Loch, Marta Grzechowiak, Mariusz Jaskolski
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Chemistry
Subjects:
Class 3 L-asparaginase
ReAV
enzymatic mechanism
amidohydrolase
enzyme kinetics
Rhizobium etli
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1373312/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2024.1373312/full

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