A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice

A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice

Human metapneumovirus (HMPV) is a common virus associated with acute respiratory distress syndrome in pediatric patients. There are no HMPV vaccines or therapeutics that have been approved for prevention or treatment. In this study, we constructed a novel recombinant influenza virus carrying partial...

Full description

Bibliographic Details
Main Authors: Tian Chongyu, Lei Guanglin, Sun Fang, Deng Zhuoya, Yang Hao, Li Cong, Li Xinyu, He Wei, Tan Lingyun, Niu Yan, Yang Penghui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Microbiology
Subjects:
influenza virus
RG technology
HMPV
fusion protein
HMPV vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1012873/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1012873/full

Similar Items