The Indirect Antiglobulin (Coombs’) Test Is Specific but Less Sensitive Than the Direct Antiglobulin Test for Detecting Anti-Erythrocytic Autoantibodies and Thereby Immune-Mediated Hemolytic Anemia in Dogs

The immunodiagnostic assessment of dogs suspected of having immune-mediated hemolytic anemia (IMHA) is based on persistent autoagglutination of erythrocytes (after three saline washes), marked spherocytosis, and a positive direct antiglobulin (Coombs’) test (DAT). However, the value of using the ind...

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Bibliographic Details
Main Authors: Nadine Idalan, Elisabeth Müller, Urs Giger
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Veterinary Sciences
Subjects:
Online Access:https://www.mdpi.com/2306-7381/10/7/415