Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancer

<p>Abstract</p> <p>Background</p> <p>Lymphovascular invasion (LVI) and lymph node metastasis are conventional pathological factors associated with an unfavorable prognosis of urothelial carcinoma of the upper urinary tract (UC-UUT), but little is known about the molecul...

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Bibliographic Details
Main Authors: Abe Hideyuki, Kambara Tsunehito, Furuya Nobutaka, Nakanishi Kimihiro, Shirataki Hiromichi, Kamai Takao, Oyama Tetsunari, Yoshida Ken-Ichiro
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/164