Chemopreventive effect of the polysaccharides from Grifola frondosa in colitis-associated colorectal cancer by modulating the Wnt/β-catenin/GSK-3β signaling pathway in C57BL/6 mice

The aim of this study was to analyze the preventive effect of water-soluble polysaccharides in the maitake mushrooms (Grifola frondosa) fruiting body (GFP) on colon cancer in high-fat (HF) mice and WIDR cells. In vivo, the administration of GFP decreased colon myeloperoxidase (MPO) activity and dise...

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Bibliographic Details
Main Authors: Meng Meng, Mingzhu Guo, Pei Wang, Ran Han, Jiaping Zhou, Chunling Wang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461930502X