SARS-CoV-2 spike-specific TFH cells exhibit unique responses in infected and vaccinated individuals

SARS-CoV-2 spike-specific TFH cells exhibit unique responses in infected and vaccinated individuals

Abstract Long-term humoral immunity to SARS-CoV-2 is essential for preventing reinfection. The production of neutralizing antibody (nAb) and B cell differentiation are tightly regulated by T follicular help (TFH) cells. However, the longevity and functional role of TFH cell subsets in COVID-19 conva...

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Bibliographic Details
Main Authors: Rongzhang He, Xingyu Zheng, Jian Zhang, Bo Liu, Qijie Wang, Qian Wu, Ziyan Liu, Fangfang Chang, Yabin Hu, Ting Xie, Yongchen Liu, Jun Chen, Jing Yang, Shishan Teng, Rui Lu, Dong Pan, You Wang, Liting Peng, Weijin Huang, Velislava Terzieva, Wenpei Liu, Youchun Wang, Yi-Ping Li, Xiaowang Qu
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01650-x

Internet

https://doi.org/10.1038/s41392-023-01650-x

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