Amyloid-Like Aggregation in Native Protein and its Suppression in the Bio-Conjugated Counterpart

Prevention of protein aggregation and thus stabilization of proteins has large biological and biotechnological implications. Here we introduce Dynamic Light Scattering (DLS) and DLS-based microrheology to show how native bovine serum albumin (nBSA) forms amyloid fibrils in weakly denaturing conditio...

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Bibliographic Details
Main Authors: Anasua Mukhopadhyay, Iliya D. Stoev, David. A. King, Kamendra P. Sharma, Erika Eiser
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.924864/full