Design, Synthesis, and Antitumor Activity Evaluation of Artemisinin Bivalent Ligands

Design, Synthesis, and Antitumor Activity Evaluation of Artemisinin Bivalent Ligands

Five artemisinin bivalent ligands molecules <b>4a</b>–<b>4e</b> were designed, synthesized, and confirmed by <sup>1</sup>H NMR, <sup>13</sup>C NMR, and low-resolution mass spectrometry, and the bioactivities of the target compounds were investigated ag...

Full description

Bibliographic Details
Main Authors: Hui Zhong, Qi Jiang, Cong Wu, Huanghe Yu, Bin Li, Xudong Zhou, Ronggeng Fu, Wei Wang, Wenbing Sheng
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
artemisinin
bivalent ligands
multi-target molecular docking
antitumor target protein
antitumor activity
Online Access:https://www.mdpi.com/1420-3049/29/2/409

Internet

https://www.mdpi.com/1420-3049/29/2/409

Similar Items