GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds
With disease-modifying compounds targeting alpha-synuclein available in clinical trials, patient stratification according to alpha-synuclein-specific enrichment strategies is a much-needed prerequisite. Such a scenario will be exemplified for GBA, one major genetic risk factor that is specifically a...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2020-09-01
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Series: | Frontiers in Cell and Developmental Biology |
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Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2020.562522/full |