A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner

A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner

ABSTRACT Coinfections shape immunity and influence the development of inflammatory diseases, resulting in detrimental or beneficial outcome. Coinfections with concurrent Plasmodium species can alter malaria clinical evolution, and malaria infection itself can modulate autoimmune reactions. Yet, the...

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Bibliographic Details
Main Authors: Ali Hassan, Myriam F. Wlodarczyk, Mehdi Benamar, Emilie Bassot, Anna Salvioni, Sahar Kassem, Antoine Berry, Abdelhadi Saoudi, Nicolas Blanchard
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
CD4 T cell
RNA virus
autoimmunity
coinfection
dendritic cells
inflammation
Online Access:https://journals.asm.org/doi/10.1128/mBio.03394-19

Internet

https://journals.asm.org/doi/10.1128/mBio.03394-19

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