A network-based approach for predicting missing pathway interactions.

Embedded within large-scale protein interaction networks are signaling pathways that encode response cascades in the cell. Unfortunately, even for well-studied species like S. cerevisiae, only a fraction of all true protein interactions are known, which makes it difficult to reason about the exact f...

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Bibliographic Details
Main Authors: Saket Navlakha, Anthony Gitter, Ziv Bar-Joseph
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3420932?pdf=render