Epithelial Na+ Channel: Reciprocal Control by COMMD10 and Nedd4-2

Epithelial Na+ Channel: Reciprocal Control by COMMD10 and Nedd4-2

Optimal function of the epithelial sodium channel (ENaC) in the distal nephron is key to the kidney’s long-term control of salt homeostasis and blood pressure. Multiple pathways alter ENaC cell surface populations, including correct processing and trafficking in the secretory pathway to the cell sur...

Full description

Bibliographic Details
Main Authors: Adam W. Ware, Tanya T. Cheung, Sahib Rasulov, Ezra Burstein, Fiona J. McDonald
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physiology
Subjects:
ENaC
protein trafficking
kidney
ubiquitin
transferrin
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00793/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00793/full

Similar Items