Direct regulation of the voltage sensor of HCN channels by membrane lipid compartmentalization
Abstract Ion channels function within a membrane environment characterized by dynamic lipid compartmentalization. Limited knowledge exists regarding the response of voltage-gated ion channels to transmembrane potential within distinct membrane compartments. By leveraging fluorescence lifetime imagin...
Main Authors: | Lucas J. Handlin, Gucan Dai |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-42363-7 |
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