Fitness of Escherichia coli during urinary tract infection requires gluconeogenesis and the TCA cycle.

Microbial pathogenesis studies traditionally encompass dissection of virulence properties such as the bacterium's ability to elaborate toxins, adhere to and invade host cells, cause tissue damage, or otherwise disrupt normal host immune and cellular functions. In contrast, bacterial metabolism...

Full description

Bibliographic Details
Main Authors: Christopher J Alteri, Sara N Smith, Harry L T Mobley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2680622?pdf=render