Sulforaphane ameliorates bisphenol A-induced hepatic lipid accumulation by inhibiting endoplasmic reticulum stress

Abstract The aim of the present study was to investigate the role of endoplasmic reticulum (ER) stress in bisphenol A (BPA) – induced hepatic lipid accumulation as well as the protective effects of Sulforaphane (SFN) in this process. Human hepatocyte cell line (LO2) and C57/BL6J mice were used to ex...

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Bibliographic Details
Main Authors: Lixia Hong, Yide Xu, Dongdong Wang, Qi Zhang, Xiaoting Li, Chunfeng Xie, Jieshu Wu, Caiyun Zhong, Jinyan Fu, Shanshan Geng
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28395-5