DCX knockout ferret reveals a neurogenic mechanism in cortical development

Summary: Lissencephaly is a rare brain malformation for which our understanding remains limited due to the absence of suitable animal models that accurately represent human phenotypes. Here, we establish doublecortin (DCX) knockout ferrets as a model that faithfully replicates key features of the di...

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Bibliographic Details
Main Authors: Wei Wang, Chonghai Yin, Shaonan Wen, Zeyuan Liu, Bosong Wang, Bo Zeng, Le Sun, Xin Zhou, Suijuan Zhong, Junjing Zhang, Wenji Ma, Qian Wu, Xiaoqun Wang
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724008374