Design of super-elastic biodegradable scaffolds with longitudinally oriented microchannels and optimization of the channel size for Schwann cell migration

We newly designed super-elastic biodegradable scaffolds with longitudinally oriented microchannels for repair and regeneration of peripheral nerve defects. Four-armed poly(ε-caprolactone-co-D,L-lactide)s (P(CL-co-DLLA)s) were synthesized by ring-opening copolymerization of CL and DLLA from terminal...

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Bibliographic Details
Main Author: Koichiro Uto, Takanari Muroya, Michio Okamoto, Hiroyuki Tanaka, Tsuyoshi Murase, Mitsuhiro Ebara and Takao Aoyagi
Format: Article
Language:English
Published: Taylor & Francis Group 2012-01-01
Series:Science and Technology of Advanced Materials
Online Access:http://dx.doi.org/10.1088/1468-6996/13/6/064207