Divergence Entropy-Based Evaluation of Hydrophobic Core in Aggressive and Resistant Forms of Transthyretin

Divergence Entropy-Based Evaluation of Hydrophobic Core in Aggressive and Resistant Forms of Transthyretin

The two forms of transthyretin differing slightly in the tertiary structure, despite the presence of five mutations, show radically different properties in terms of susceptibility to the amyloid transformation process. These two forms of transthyretin are the object of analysis. The search for the s...

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Bibliographic Details
Main Authors: Mateusz Banach, Katarzyna Stapor, Piotr Fabian, Leszek Konieczny, Irena Roterman
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Entropy
Subjects:
amyloid
transthyretin
hydrophobicity
hydrophobic core
early stage of folding
micellarization
Online Access:https://www.mdpi.com/1099-4300/23/4/458

Internet

https://www.mdpi.com/1099-4300/23/4/458

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