Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways

Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways

Toxin-antitoxin (TA) modules are bacterial regulatory switches that facilitate conflicting outcomes for cells by promoting a pro-survival phenotypic adaptation and/or by directly mediating cell death, all through the toxin activity upon degradation of antitoxin. Intensive study has revealed specific...

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Bibliographic Details
Main Authors: Meenakumari Muthuramalingam, John C. White, Christina R. Bourne
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Toxins
Subjects:
toxin-antitoxin
phenotypic changes
persister cells
post-segregational killing
bacterial physiology
environmental adaptation
cellular proteases
protease adaptors
Online Access:http://www.mdpi.com/2072-6651/8/7/214

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http://www.mdpi.com/2072-6651/8/7/214

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