Serum Neurofilament Light Chain Levels May Be a Marker of Lower Motor Neuron Damage in Amyotrophic Lateral Sclerosis

Serum Neurofilament Light Chain Levels May Be a Marker of Lower Motor Neuron Damage in Amyotrophic Lateral Sclerosis

Objectives The aims of this study were to investigate whether serum neurofilament light chain (NfL) levels were correlated with the severity of the axonal degeneration of lower motor neurons (LMNs) in the early symptomatic phase of amyotrophic lateral sclerosis (ALS). Methods In this prospective stu...

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Bibliographic Details
Main Authors: Linjing Zhang, Tuo Ji, Chujun Wu, Shuo Zhang, Lu Tang, Nan Zhang, Xiangyi Liu, Dongsheng Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Neurology
Subjects:
NfL
amyotrophic lateral sclerosis
axonal degeneration
CMAPs
EMG - electromyogram
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.833507/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.833507/full

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