Multiplexed RNA profiling by regenerative catalysis enables blood-based subtyping of brain tumors

Abstract Current technologies to subtype glioblastoma (GBM), the most lethal brain tumor, require highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve direct and multiplexed profiling of circulating RNAs in extracellular vesicles for blood-based GBM characteriz...

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Bibliographic Details
Main Authors: Yan Zhang, Chi Yan Wong, Carine Z. J. Lim, Qingchang Chen, Zhonglang Yu, Auginia Natalia, Zhigang Wang, Qing You Pang, See Wee Lim, Tze Ping Loh, Beng Ti Ang, Carol Tang, Huilin Shao
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39844-0