The Loss of <i>focA</i> Gene Increases the Ability of <i>Salmonella</i> Enteritidis to Exit from Macrophages and Boosts Early Extraintestinal Spread for Systemic Infection in a Mouse Model

The Loss of <i>focA</i> Gene Increases the Ability of <i>Salmonella</i> Enteritidis to Exit from Macrophages and Boosts Early Extraintestinal Spread for Systemic Infection in a Mouse Model

<i>Salmonella</i> Enteritidis (SE) can spread from the intestines to cause systemic infection, mainly involving macrophages. Intramacrophage <i>Salmonella</i> exits and reinfects neighboring cells, leading to severe disease. <i>Salmonella</i> genes involved in exi...

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Bibliographic Details
Main Authors: Ran Gao, Jian Zhang, Haoyu Geng, Yaonan Wang, Xilong Kang, Shizhong Geng, Xin’an Jiao, Paul Barrow
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Microorganisms
Subjects:
<i>Salmonella</i> Enteritidis
<i>focA</i> gene
exit from macrophages
extraintestinal spread
systemic infection
virulence
Online Access:https://www.mdpi.com/2076-2607/10/8/1557

Internet

https://www.mdpi.com/2076-2607/10/8/1557

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