Iron-tracking strategies: Chaperones capture iron in the cytosolic labile iron pool

Iron-tracking strategies: Chaperones capture iron in the cytosolic labile iron pool

Cells express hundreds of iron-dependent enzymes that rely on the iron cofactors heme, iron-sulfur clusters, and mono-or di-nuclear iron centers for activity. Cells require systems for both the assembly and the distribution of iron cofactors to their cognate enzymes. Proteins involved in the binding...

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Bibliographic Details
Main Authors: Caroline C. Philpott, Olga Protchenko, Yubo Wang, Lorena Novoa-Aponte, Andres Leon-Torres, Samantha Grounds, Amber J. Tietgens
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
poly C binding protein1
PCBP1
ferroptosis
ferroportin
enteroid
ferritin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1127690/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1127690/full

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