A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.
BACKGROUND:Tissue inhibitor of metalloproteinases-1 (TIMP-1) displays pleiotropic activities, both dependent and independent of its inhibitory activity on matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMP-1 is strongly upregulated in reactive astrocytes and cortical neurons...
Główni autorzy: | , , , , , , , , , , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2009-12-01
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Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC2788270?pdf=render |