Macrophage metallothioneins participate in the antileishmanial activity of antimonials
Host cell functions that participate in the pharmacokinetics and pharmacodynamics (PK/PD) of drugs against intracellular pathogen infections are critical for drug efficacy. In this study, we investigated whether macrophage mechanisms of xenobiotic detoxification contribute to the elimination of intr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Parasitology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpara.2023.1242727/full |