Cerebrospinal fluid biomarkers of axonal and synaptic degeneration in a population-based sample

Cerebrospinal fluid biomarkers of axonal and synaptic degeneration in a population-based sample

Abstract Background Neurofilament light (NfL) and neurogranin (Ng) are promising candidate AD biomarkers, reflecting axonal and synaptic damage, respectively. Since there is a need to understand the synaptic and axonal damage in preclinical Alzheimer’s disease (AD), we aimed to determine the cerebro...

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Bibliographic Details
Main Authors: Maya Arvidsson Rådestig, Ingmar Skoog, Tobias Skillbäck, Henrik Zetterberg, Jürgen Kern, Anna Zettergren, Ulf Andreasson, Hanna Wetterberg, Silke Kern, Kaj Blennow
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Cerebrospinal fluid
CSF
biomarkers
Neurolfilament light
NfL
Online Access:https://doi.org/10.1186/s13195-023-01193-x

Internet

https://doi.org/10.1186/s13195-023-01193-x

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