Toxicity assessment of silica coated iron oxide nanoparticles and biocompatibility improvement by surface engineering.

Toxicity assessment of silica coated iron oxide nanoparticles and biocompatibility improvement by surface engineering.

We have studied in vitro toxicity of iron oxide nanoparticles (NPs) coated with a thin silica shell (Fe3O4/SiO2 NPs) on A549 and HeLa cells. We compared bare and surface passivated Fe3O4/SiO2 NPs to evaluate the effects of the coating on the particle stability and toxicity. NPs cytotoxicity was inve...

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Bibliographic Details
Main Authors: Maria Ada Malvindi, Valeria De Matteis, Antonio Galeone, Virgilio Brunetti, George C Anyfantis, Athanassia Athanassiou, Roberto Cingolani, Pier Paolo Pompa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897540?pdf=render

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http://europepmc.org/articles/PMC3897540?pdf=render

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