In-cell protease assay systems based on trans-localizing molecular beacon proteins using HCV protease as a model system.

In-cell protease assay systems based on trans-localizing molecular beacon proteins using HCV protease as a model system.

This study describes a sensitive in-cell protease detection system that enables direct fluorescence detection of a target protease and its inhibition inside living cells. This live-cell imaging system provides a fluorescent molecular beacon protein comprised of an intracellular translocation signal...

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Bibliographic Details
Main Authors: Jeong Hee Kim, Min Jun Lee, Inhwan Hwang, Hyun Jin Hwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3605327?pdf=render

Internet

http://europepmc.org/articles/PMC3605327?pdf=render

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