Astaxanthin ameliorates dopaminergic neuron damage in paraquat-induced SH-SY5Y cells and mouse models of Parkinson's disease

Astaxanthin ameliorates dopaminergic neuron damage in paraquat-induced SH-SY5Y cells and mouse models of Parkinson's disease

Parkinson’s disease (PD) is the second largest neurodegenerative disorder caused by the decreased number of dopaminergic (DAc) neurons in the substantia nigra pars compacta (SNpc). There is evidence that oxidative stress can contribute degeneration of DAc neurons in SNpc which is mainly caused by ap...

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Bibliographic Details
Main Authors: Lei Wang, Kunliang Lu, Xingyue Lou, Shenghui Zhang, Wenxin Song, Ranran Li, Lujing Geng, Binfeng Cheng
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain Research Bulletin
Subjects:
Astaxanthin
Parkinson’s disease
Paraquat
Oxidative stress
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001879

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http://www.sciencedirect.com/science/article/pii/S0361923023001879

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