A comparison of methods for detecting DNA methylation from long-read sequencing of human genomes
Abstract Background Long-read sequencing can enable the detection of base modifications, such as CpG methylation, in single molecules of DNA. The most commonly used methods for long-read sequencing are nanopore developed by Oxford Nanopore Technologies (ONT) and single molecule real-time (SMRT) sequ...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-024-03207-9 |