Integrated transcriptome study of the tumor microenvironment for treatment response prediction in male predominant hypopharyngeal carcinoma

Integrated transcriptome study of the tumor microenvironment for treatment response prediction in male predominant hypopharyngeal carcinoma

Many patients with hypopharyngeal carcinoma (HPC) do not respond to first-line combination therapy. Here, the authors analyse the tumour and the tumour microenvironment of HPC patients treated with combination therapy using single-cell RNA-seq, and train a classifier to distinguish responders based...

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Bibliographic Details
Main Authors: Yang Zhang, Gan Liu, Minzhen Tao, Hui Ning, Wei Guo, Gaofei Yin, Wen Gao, Lifei Feng, Jin Gu, Zhen Xie, Zhigang Huang
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37159-8

Internet

https://doi.org/10.1038/s41467-023-37159-8

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