Prediction of missing common genes for disease pairs using network based module separation on incomplete human interactome

Prediction of missing common genes for disease pairs using network based module separation on incomplete human interactome

Abstract Background Identification of common genes associated with comorbid diseases can be critical in understanding their pathobiological mechanism. This work presents a novel method to predict missing common genes associated with a disease pair. Searching for missing common genes is formulated as...

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Bibliographic Details
Main Authors: Pakeeza Akram, Li Liao
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Disease module separation
Optimization
Interactome
Missing gene
Comorbidity
Online Access:http://link.springer.com/article/10.1186/s12864-017-4272-7

Internet

http://link.springer.com/article/10.1186/s12864-017-4272-7

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