The Autophagy Nucleation Factor ATG9 Forms Nanoclusters with the HIV-1 Receptor DC-SIGN and Regulates Early Antiviral Autophagy in Human Dendritic Cells

The Autophagy Nucleation Factor ATG9 Forms Nanoclusters with the HIV-1 Receptor DC-SIGN and Regulates Early Antiviral Autophagy in Human Dendritic Cells

Dendritic cells (DC) are critical cellular mediators of host immunity, notably by expressing a broad panel of pattern recognition receptors. One of those receptors, the C-type lectin receptor DC-SIGN, was previously reported as a regulator of endo/lysosomal targeting through functional connections w...

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Bibliographic Details
Main Authors: Laure Papin, Martin Lehmann, Justine Lagisquet, Ghizlane Maarifi, Véronique Robert-Hebmann, Christophe Mariller, Yann Guerardel, Lucile Espert, Volker Haucke, Fabien P. Blanchet
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
dendritic cells
HIV-1
DC-SIGN
innate immunity
Online Access:https://www.mdpi.com/1422-0067/24/10/9008

Internet

https://www.mdpi.com/1422-0067/24/10/9008

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