Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line

Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line

Purpose: To investigate the downregulation of high mobility group AT-hook 2 (HMGA2)expression by small interfering RNAs (siRNAs) in PC3 prostate cancer cell line. HMGA2belongs to the non-histone chromatin-binding protein family that serves as a crucial regulator ofgene transcription. The overexpress...

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Bibliographic Details
Main Authors: Shima Khajouee, Elham Baghbani, Ali Mohammadi, Behzad Mansoori, Dariush Shanehbandi, Khalil Hajiasgharzadeh, Behzad Baradaran
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-03-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
hmga2
gene therapy
small interfering rna
prostate cancer
apoptosis assay
cell migration
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-398.pdf

Internet

https://apb.tbzmed.ac.ir/PDF/apb-12-398.pdf

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