Costimulators expressed on human endothelial cells modulate antigen-dependent recruitment of circulating T lymphocytes

Endothelial cells (ECs) can present antigens to circulating effector memory T cells (TEM) and to regulatory T cells (T regs), triggering antigen-specific extravasation at specific sites where foreign antigens are introduced, e.g. by infection or transplantation. We model human antigen-induced transe...

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Bibliographic Details
Main Authors: Thomas D. Manes, Vivian Wang, Jordan S. Pober
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1016361/full