Nitric oxide mediates inhibitory effect of losartan on angiotensin-induced contractions in hamster but not rat aorta
We investigated a possible contribution of nitric oxide (NO) and prostaglandins to the inhibitory effect of losartan on contractions to Ang I (10 -6 M) and Ang II (10 -7 M) with or without L-NAME (10 -4 M) or indomethacin (10 -5 M) in the aorta of WKY, SHR and hamster (n=7 each). Rings of thoracic a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2000-06-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.3317/jraas.2000.023 |