IL-23 Contributes to Campylobacter jejuni-Induced Intestinal Pathology via Promoting IL-17 and IFNγ Responses by Innate Lymphoid Cells

IL-23 Contributes to Campylobacter jejuni-Induced Intestinal Pathology via Promoting IL-17 and IFNγ Responses by Innate Lymphoid Cells

Human pathogen Campylobacter jejuni is a significant risk factor for the development of long-term intestinal dysfunction although the cellular and molecular mechanisms remain scantily defined. IL-23 is an emerging therapeutic target for the treatment of inflammatory intestinal diseases, however its...

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Bibliographic Details
Main Authors: Xi Jing, Anna A. Korchagina, Sergey A. Shein, Wayne T. Muraoka, Ekaterina Koroleva, Alexei V. Tumanov
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
Campylobacter jejuni
colitis
innate lymphoid cells
interleukin-23
Campylobacteriosis
IL-10
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.579615/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.579615/full

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