Interaction of a Novel Alternatively Spliced Variant of <i>HSD11B1L</i> with Parkin Enhances the Carcinogenesis Potential of Glioblastoma: Peiminine Interferes with This Interaction

Interaction of a Novel Alternatively Spliced Variant of <i>HSD11B1L</i> with Parkin Enhances the Carcinogenesis Potential of Glioblastoma: Peiminine Interferes with This Interaction

Glioblastoma (GBM) is a primary brain tumor of unknown etiology. It is extremely aggressive, incurable and has a short average survival time for patients. Therefore, understanding the precise molecular mechanisms of this diseases is essential to establish effective treatments. In this study, we clon...

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Bibliographic Details
Main Authors: Ru-Huei Fu, Syuan-Yu Hong, Chia-Wen Tsai, Shih-Ping Liu, Shao-Chih Chiu, Meng-Zhen Wu, Woei-Cherng Shyu, Shinn-Zong Lin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
glioblastoma
alternative splicing
hydroxysteroid 11-β-dehydrogenase 1 like gene (HSD11B1L)
proliferation
migration
invasion
Online Access:https://www.mdpi.com/2073-4409/12/6/894

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https://www.mdpi.com/2073-4409/12/6/894

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