Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway
Objective(s): Excess intake of a high-fatty diet (HFD) together with zymosan administration mediates vasculitis response which leads to impaired serum lipid levels and causes arterial stiffness. In the development of new cholesterol-lowering medications, PCSK9 inhibitor (proprotein convertase subtil...
| المؤلفون الرئيسيون: | , , , |
|---|---|
| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Mashhad University of Medical Sciences
2022-05-01
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| سلاسل: | Iranian Journal of Basic Medical Sciences |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ijbms.mums.ac.ir/article_20184_08cc21fdddef2aacc5bad6fe66520795.pdf |