Association between <i>SMAD4</i> Mutations and <i>GATA6</i> Expression in Paired Pancreatic Ductal Adenocarcinoma Tumor Specimens: Data from Two Independent Molecularly-Characterized Cohorts

Association between <i>SMAD4</i> Mutations and <i>GATA6</i> Expression in Paired Pancreatic Ductal Adenocarcinoma Tumor Specimens: Data from Two Independent Molecularly-Characterized Cohorts

Several molecular biomarkers have been identified to guide induction treatment selection for localized pancreatic ductal adenocarcinoma (PDAC). <i>SMAD4</i> alterations and low <i>GATA6</i> expression/modified “Moffitt” basal-like phenotype have each been associated with infe...

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Bibliographic Details
Main Authors: Joshua D. Greendyk, William E. Allen, H. Richard Alexander, Toni Beninato, Mariam F. Eskander, Miral S. Grandhi, Timothy J. Kennedy, Russell C. Langan, Jason C. Maggi, Subhajyoti De, Colin M. Court, Brett L. Ecker
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
pancreatic ductal adenocarcinoma
<i>SMAD4</i>
<i>GATA6</i>
basal-like
precision oncology
molecular biomarker
Online Access:https://www.mdpi.com/2227-9059/11/11/3058

Internet

https://www.mdpi.com/2227-9059/11/11/3058

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