Endoplasmic reticulum stressed HNSCC cell-derived exosomal miR-26a-5p promotes PD-L1 expression in macrophage through PTEN/AKT signaling pathway

Endoplasmic reticulum stressed HNSCC cell-derived exosomal miR-26a-5p promotes PD-L1 expression in macrophage through PTEN/AKT signaling pathway

Objective To investigate the impact of exosomal miRNAs derived from endoplasmic reticulum-stressed (ERS) head and neck squamous cell carcinoma (HNSCC) cells on macrophages. Methods This study was reviewed and approved by the Ethics Committee. The expression levels of ERS-associated proteins, includi...

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Bibliographic Details
Main Authors: JIAO Pengfei, WANG Zeyu, WU Heming, YAO Siyue, WANG Huilin, YAO Enhui, ZHANG Yuyao, YUAN Yi, ZHONG Yi
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2024-01-01
Series:口腔疾病防治
Subjects:
head and neck squamous cell carcinoma
endoplasmic reticulum stress
exosome
mir-26a-5p
macrophage
programmed death receptor ligand 1
phosphate and tension homology deleted on chromsome ten
protein kinase b
Online Access:https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2024.01.003

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https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2024.01.003

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