Genetic Variants of the DSF Quorum Sensing System in Stenotrophomonas maltophilia Influence Virulence and Resistance Phenotypes Among Genotypically Diverse Clinical Isolates

Genetic Variants of the DSF Quorum Sensing System in Stenotrophomonas maltophilia Influence Virulence and Resistance Phenotypes Among Genotypically Diverse Clinical Isolates

The pathogenicity of Stenotrophomonas maltophilia is regulated in part by its quorum sensing (QS) system. The main QS signaling molecule in S. maltophilia is known as diffusible signal factor (DSF), and the rpf gene cluster is responsible for its synthesis and perception. Two cluster variants have b...

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Bibliographic Details
Main Authors: Daniel Yero, Pol Huedo, Oscar Conchillo-Solé, Sònia Martínez-Servat, Uwe Mamat, Xavier Coves, Ferran Llanas, Ignasi Roca, Jordi Vila, Ulrich E. Schaible, Xavier Daura, Isidre Gibert
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
quorum sensing (QS)
diffusible signal factor (DSF)
MLST (multilocus sequence typing)
rpf cluster
biofilm
antibiotic resistance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01160/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01160/full

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