The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading.

The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading.

Motility of normal and transformed cells within and across tissues requires specialized subcellular structures, e.g. membrane ruffles, lamellipodia and podosomes, which are generated by dynamic rearrangements of the actin cytoskeleton. Because the formation of these sub-cellular structures is comple...

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Bibliographic Details
Main Authors: Árpád Lányi, Mónika Baráth, Zalán Péterfi, Gábor Bogel, Anna Orient, Tünde Simon, Eniko Petrovszki, Katalin Kis-Tóth, Gábor Sirokmány, Éva Rajnavölgyi, Cox Terhorst, László Buday, Miklós Geiszt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3160312?pdf=render

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http://europepmc.org/articles/PMC3160312?pdf=render

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