New Trifluoromethyl Triazolopyrimidines as Anti-<em>Plasmodium</em> <em>falciparum</em> Agents

New Trifluoromethyl Triazolopyrimidines as Anti-<em>Plasmodium</em> <em>falciparum</em> Agents

According to the World Health Organization, half of the World’s population, approximately 3.3 billion people, is at risk for developing malaria. Nearly 700,000 deaths each year are associated with the disease. Control of the disease in humans still relies on chemotherapy. Drug resistance is a limiti...

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Bibliographic Details
Main Authors: Núbia Boechat, Luiz C. S. Pinheiro, Thiago S. Silva, Anna C. C. Aguiar, Alcione S. Carvalho, Monica M. Bastos, Carolina C. P. Costa, Sergio Pinheiro, Angelo C. Pinto, Jorge S. Mendonça, Karen D. B. Dutra, Alessandra L. Valverde, Osvaldo A. Santos-Filho, Isabela P. Ceravolo, Antoniana U. Krettli
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Molecules
Subjects:
triazolopyrimidine
trifluoromethyl
malaria
<em>P. falciparum</em>
<em>Pf</em>DHODH
Online Access:http://www.mdpi.com/1420-3049/17/7/8285

Internet

http://www.mdpi.com/1420-3049/17/7/8285

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